Centrifuge-based deterministic lateral displacement separation
نویسندگان
چکیده
منابع مشابه
Continuous particle separation through deterministic lateral displacement.
We report on a microfluidic particle-separation device that makes use of the asymmetric bifurcation of laminar flow around obstacles. A particle chooses its path deterministically on the basis of its size. All particles of a given size follow equivalent migration paths, leading to high resolution. The microspheres of 0.8, 0.9, and 1.0 micrometers that were used to characterize the device were s...
متن کاملSeparation of deformable particles in deterministic lateral displacement devices.
Using numerical simulations, we study the separation of deformable bodies, such as capsules, vesicles, and cells, in deterministic lateral displacement devices, also known as bump arrays. These arrays comprise regular rows of obstacles such as micropillars whose arrangements are shifted between adjacent rows by a fixed amount. We show that, in addition to the zigzag and laterally displaced traj...
متن کاملDirectional locking in deterministic lateral-displacement microfluidic separation systems.
We analyze the trajectory of suspended spherical particles moving through a square array of obstacles, in the deterministic limit and at zero Reynolds number. We show that in the dilute approximation of widely separated obstacles, the average motion of the particles is equivalent to the trajectory followed by a point particle moving through an array of obstacles with an effective radius. The ef...
متن کاملParticle Separation with Deterministic Lateral Displacement ( DLD ) : The Anisotropy Effect †
Deterministic lateral displacement (DLD) is a passive and label-free microfluidic separation technique with a strong potential for biological sample preparation purposes. Numerical and experimental models have been proposed so far to predict the particle behavior in DLD channels. However, they do not take into account the influence of the pillar anisotropy that induces a secondary pressure grad...
متن کاملDeterministic lateral displacement for particle separation: a review.
Deterministic lateral displacement (DLD), a hydrodynamic, microfluidic technology, was first reported by Huang et al. in 2004 to separate particles on the basis of size in continuous flow with a resolution of down to 10 nm. For 10 years, DLD has been extensively studied, employed and modified by researchers in terms of theory, design, microfabrication and application to develop newer, faster an...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Microfluidics and Nanofluidics
سال: 2016
ISSN: 1613-4982,1613-4990
DOI: 10.1007/s10404-015-1686-x